| All Time Matchup | DET - 3 || SF - 1 || 0 ties
Last Game: Week 19, 1988 - San Francisco 49ers - 27 @ Detroit Lions - 33 | | Record | 8-1-0 (3-1-0 Away) |
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| Coach | Nick Miller |
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| Off Scheme | WestCoastHybrid |
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| Def Scheme | D34Hybrid |
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| Offense | Overall - 3659(1) : Pass - 2346(3) : Rush - 1313(7) |
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| Defense | Overall - 3088(9) : Pass - 2293(18) : Rush - 795(2) |
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| Leading Passer | John Elway - 2243 |
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| Leading Rusher | John Elway - 527 |
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| Leading Receiver | Mike Williams - 726 |
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| Leading Tackler | Lawyer Milloy - 66 |
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| Turnovers | 19 Take Aways / 13 Turn Overs (+6) |
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| Penalties | 50 For 425 Yards |
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| | Record | 6-3-0 (4-0-0 Home) |
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| Coach | Grace Savage |
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| Off Scheme | SpreadHybrid |
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| Def Scheme | D34 |
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| Offense | Overall - 3606(2) : Pass - 2459(2) : Rush - 1147(10) |
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| Defense | Overall - 2942(4) : Pass - 1738(2) : Rush - 1204(13) |
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| Leading Passer | Bernie Kosar - 2459 |
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| Leading Rusher | Joe Morris - 526 |
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| Leading Receiver | Anthony Carter - 728 |
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| Leading Tackler | Freddie Joe Nunn - 68 |
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| Turnovers | 13 Take Aways / 3 Turn Overs (+10) |
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| Penalties | 41 For 369 Yards |
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| Last Game Starters |
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Detroit Lions Offense| Quarterback | John Elway |
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| Running Backs | Freeman McNeil - James Jones FB II |
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| Receivers | Mike Williams - Jermaine Lewis |
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| Tight End | Isaiah Likely |
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| Offensive Line | Bruce Matthews - Jim Sweeney - Kevin Glover - Dean Miraldi - Jimbo Covert |
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Detroit Lions Defense
| Defensive Line | George Karlaftis - Keith Millard - Richard Dent |
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| Linebackers | Devin Lloyd - David Harris - Duane Bickett - Randall Godfrey |
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| Cornerbacks | Eugene Daniel - Cam Taylor-Britt |
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| Safeties | Kyle Hamilton - Lawyer Milloy |
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| Kicker / Punter | Matt Stover - Jordan Stout |
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San Francisco 49ers Offense| Quarterback | Bernie Kosar |
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| Running Backs | Joe Morris - Mike Rozier |
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| Receivers | Anthony Carter - Jerry Rice |
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| Tight End | Steve Jordan |
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| Offensive Line | Willie Anderson - Mike Munchak - Bart Oates - Dylan Parham - James Williams |
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San Francisco 49ers Defense
| Defensive Line | Charles Mann - John Jurkovic - Leonard Marshall |
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| Linebackers | Nik Bonitto - Mike Merriweather - Johnny Rembert - Freddie Joe Nunn |
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| Cornerbacks | Frank Minnifield - Ray Horton |
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| Safeties | Reed Blankenship - Dennis Smith |
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| Kicker / Punter | Scott Blanton - Jon Ryan |
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| Injuries |
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Detroit Lions Injuries
| John Elway (QB) | Hyper Extended Knee (Out (1-2 weeks)) |
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| Freeman McNeil (RB) | Dislocated Shoulder (Probable) |
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| Mark Robinson (CB) | Sprained Ankle (Doubtful) |
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| Jermaine Lewis (WR) | Bruised Hip (Probable) |
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| Cam Taylor-Britt (CB) | Jammed Finger (Questionable) |
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San Francisco 49ers Injuries
| Frank Minnifield (CB) | Deep Thigh Bruise (Out (1-2 weeks)) |
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