| All Time Matchup | SF - 1 || DET - 3 || 0 ties
Last Game: Week 19, 1988 - San Francisco 49ers - 27 @ Detroit Lions - 33 | | Record | 4-2-0 (2-2-0 Away) |
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| Coach | Grace Savage |
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| Off Scheme | SpreadHybrid |
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| Def Scheme | D34 |
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| Offense | Overall - 2417(4) : Pass - 1614(3) : Rush - 803(10) |
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| Defense | Overall - 1915(2) : Pass - 1070(1) : Rush - 845(12) |
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| Leading Passer | Bernie Kosar - 1614 |
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| Leading Rusher | Joe Morris - 373 |
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| Leading Receiver | Anthony Carter - 477 |
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| Leading Tackler | Freddie Joe Nunn - 47 |
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| Turnovers | 7 Take Aways / 1 Turn Overs (+6) |
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| Penalties | 32 For 284 Yards |
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| | Record | 5-1-0 (3-0-0 Home) |
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| Coach | Nick Miller |
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| Off Scheme | WestCoastHybrid |
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| Def Scheme | D34Hybrid |
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| Offense | Overall - 2498(2) : Pass - 1595(4) : Rush - 903(8) |
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| Defense | Overall - 2048(7) : Pass - 1678(20) : Rush - 370(2) |
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| Leading Passer | John Elway - 1595 |
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| Leading Rusher | John Elway - 344 |
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| Leading Receiver | Mike Williams - 497 |
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| Leading Tackler | Duane Bickett - 45 |
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| Turnovers | 12 Take Aways / 7 Turn Overs (+5) |
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| Penalties | 28 For 241 Yards |
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| Last Game Starters |
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San Francisco 49ers Offense| Quarterback | Bernie Kosar |
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| Running Backs | Joe Morris - Mike Rozier |
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| Receivers | Anthony Carter - Jerry Rice |
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| Tight End | Steve Jordan |
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| Offensive Line | Willie Anderson - Mike Munchak - Bart Oates - Dylan Parham - James Williams |
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San Francisco 49ers Defense
| Defensive Line | Charles Mann - John Jurkovic - Leonard Marshall |
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| Linebackers | Nik Bonitto - Mike Merriweather - Johnny Rembert - Freddie Joe Nunn |
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| Cornerbacks | Frank Minnifield - Ray Horton |
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| Safeties | Reed Blankenship - Dennis Smith |
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| Kicker / Punter | Scott Blanton - Jon Ryan |
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Detroit Lions Offense| Quarterback | John Elway |
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| Running Backs | Freeman McNeil - James Jones FB II |
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| Receivers | Mike Williams - Jermaine Lewis |
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| Tight End | Isaiah Likely |
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| Offensive Line | Bruce Matthews - Jim Sweeney - Kevin Glover - Dean Miraldi - Jimbo Covert |
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Detroit Lions Defense
| Defensive Line | George Karlaftis - Keith Millard - Keith Ellison |
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| Linebackers | Devin Lloyd - David Harris - Duane Bickett - Randall Godfrey |
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| Cornerbacks | Eugene Daniel - Cam Taylor-Britt |
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| Safeties | Kyle Hamilton - Lawyer Milloy |
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| Kicker / Punter | Matt Stover - Jordan Stout |
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| Injuries |
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San Francisco 49ers Injuries
| Mike Merriweather (LB) | Deep Thigh Bruise (Questionable) |
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Detroit Lions Injuries
| David Harris (LB) | Sprained Wrist (Probable) |
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