| All Time Matchup | IND - 0 || BUF - 2 || 0 ties
Last Game: | | Record | 6-2-0 (3-1-0 Away) |
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| Coach | Tony Dungy |
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| Off Scheme | ProStyleHybrid |
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| Def Scheme | D43Hybrid |
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| Offense | Overall - 2654(16) : Pass - 1472(17) : Rush - 1182(6) |
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| Defense | Overall - 2758(9) : Pass - 1854(10) : Rush - 904(6) |
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| Leading Passer | Ken Stabler - 1361 |
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| Leading Rusher | Curt Warner - 618 |
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| Leading Receiver | Eddie Brown - 437 |
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| Leading Tackler | Emlen Tunnell - 61 |
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| Turnovers | 10 Take Aways / 10 Turn Overs (0) |
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| Penalties | 48 For 385 Yards |
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| | Record | 4-4-0 (2-3-0 Home) |
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| Coach | Marv Levy |
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| Off Scheme | SpreadHybrid |
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| Def Scheme | D43 |
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| Offense | Overall - 2708(15) : Pass - 1721(11) : Rush - 987(10) |
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| Defense | Overall - 2736(7) : Pass - 2041(15) : Rush - 695(2) |
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| Leading Passer | Mike Ngo - 1193 |
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| Leading Rusher | Greg Bell - 724 |
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| Leading Receiver | Marvin Harrison - 634 |
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| Leading Tackler | Mike Singletary - 64 |
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| Turnovers | 10 Take Aways / 5 Turn Overs (+5) |
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| Penalties | 42 For 360 Yards |
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| Last Game Starters |
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Indianapolis Colts Offense| Quarterback | Jim Kelly |
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| Running Backs | Curt Warner - Tom Rathman |
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| Receivers | Paul Warfield - Eddie Brown |
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| Tight End | Rickey Dudley |
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| Offensive Line | Jonathan Ogden - Brandon Burlsworth - Mark Tuinei - Eric Moten - Evan Neal |
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Indianapolis Colts Defense
| Defensive Line | Bruce Smith - La'Roi Glover - Bronko Nagurski - Chris Doleman |
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| Linebackers | Brian Asamoah II - Matt Millen - Jack Sanborn |
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| Cornerbacks | Dick LeBeau - Roger McCreary |
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| Safeties | Emlen Tunnell - Todd Lyght |
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| Kicker / Punter | Stephen Gostkowski - Rohn Stark |
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Buffalo Bills Offense| Quarterback | Mike Ngo |
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| Running Backs | Greg Bell - Tuffy Leemans |
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| Receivers | Marvin Harrison - Andre Reed |
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| Tight End | Pete Metzelaars |
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| Offensive Line | Anthony Munoz - Jahri Evans - Nick Mangold - Cam Jurgens - Eric Young |
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Buffalo Bills Defense
| Defensive Line | Reggie White - Russell Maryland - Darryl Grant - Simeon Rice |
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| Linebackers | Pat Swilling - Mike Singletary - Lawrence Taylor |
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| Cornerbacks | Everson Walls - Marcus Jones CB |
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| Safeties | Eugene Robinson - Nick Cross |
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| Kicker / Punter | Nick Novak - Jake Camarda |
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| Injuries |
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Indianapolis Colts Injuries
| Matt Millen (LB) | Groin Pull (Out (1-2 weeks)) |
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| Anthony Fasano (TE) | Broken Finger (Questionable) |
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| Todd Lyght (SS) | Broken Finger (Probable) |
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Buffalo Bills Injuries
| Mike Ngo (QB) | Sprained Wrist (Doubtful) |
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| Cam Jurgens (G) | Sprained Wrist (Probable) |
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