| All Time Matchup | SD - 0 || IND - 1 || 0 ties
Last Game: | | Record | 4-7-0 (2-4-0 Away) |
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| Coach | Holden McGroin |
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| Off Scheme | WestCoast |
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| Def Scheme | D43Hybrid |
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| Offense | Overall - 4202(8) : Pass - 2980(7) : Rush - 1222(15) |
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| Defense | Overall - 4179(15) : Pass - 2843(15) : Rush - 1336(9) |
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| Leading Passer | Jason Campbell - 2980 |
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| Leading Rusher | Ronnie Harmon - 700 |
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| Leading Receiver | Chris Burkett - 945 |
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| Leading Tackler | Mo Lewis - 109 |
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| Turnovers | 13 Take Aways / 13 Turn Overs (0) |
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| Penalties | 72 For 608 Yards |
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| | Record | 7-4-0 (4-2-0 Home) |
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| Coach | Tony Dungy |
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| Off Scheme | ProStyleHybrid |
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| Def Scheme | D43Hybrid |
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| Offense | Overall - 3872(13) : Pass - 2331(12) : Rush - 1541(8) |
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| Defense | Overall - 4023(13) : Pass - 2762(13) : Rush - 1261(5) |
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| Leading Passer | Ken Stabler - 1361 |
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| Leading Rusher | Curt Warner - 867 |
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| Leading Receiver | Eddie Brown - 728 |
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| Leading Tackler | Emlen Tunnell - 74 |
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| Turnovers | 14 Take Aways / 12 Turn Overs (+2) |
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| Penalties | 71 For 561 Yards |
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| Last Game Starters |
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San Diego Chargers Offense| Quarterback | Jason Campbell |
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| Running Backs | Ronnie Harmon - Michael Robinson |
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| Receivers | Chris Burkett - Garrett Wilson |
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| Tight End | Clint Didier |
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| Offensive Line | Joe Thomas - Kurt Quarterman - Joe Thomas - Rob Sims - Donald Penn |
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San Diego Chargers Defense
| Defensive Line | Darryl Tapp - Orpheus Roye - Charles Haley - Keyunta Dawson |
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| Linebackers | Fredd Young - Mo Lewis - Darren Comeaux |
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| Cornerbacks | Jack Jones - Al Harris |
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| Safeties | JT Woods - Mo Lewis |
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| Kicker / Punter | Tony Franklin - Tony Franklin |
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Indianapolis Colts Offense| Quarterback | Jim Kelly |
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| Running Backs | Curt Warner - Tom Rathman |
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| Receivers | Paul Warfield - Eddie Brown |
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| Tight End | Rickey Dudley |
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| Offensive Line | Jonathan Ogden - Eric Moten - Luke Fortner - Brandon Burlsworth - Evan Neal |
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Indianapolis Colts Defense
| Defensive Line | Chris Doleman - Bronko Nagurski - La'Roi Glover - Bruce Smith |
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| Linebackers | Troy Andersen - Jack Sanborn - Brian Asamoah II |
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| Cornerbacks | Dick LeBeau - Roger McCreary |
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| Safeties | Emlen Tunnell - Todd Lyght |
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| Kicker / Punter | Stephen Gostkowski - Rohn Stark |
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| Injuries |
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San Diego Chargers Injuries
| Chris Dressel (TE) | Dislocated Shoulder (Doubtful) |
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| Rob Sims (G) | Groin Pull (Probable) |
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| Joe Thomas (T) | Hyper Extended Knee (Doubtful) |
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Indianapolis Colts Injuries
| Matt Millen (LB) | Groin Pull (Questionable) |
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| Rickey Dudley (TE) | Bruised Hip (Probable) |
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