| All Time Matchup | BUF - 5 || NYT - 1 || 0 ties Last Game: Week 18, 1989 - Buffalo Bills - 41 @ New York Titans - 17 | | Record | 2-0-0 (1-0-0 Away) |
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| Coach | Marv Levy |
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| Off Scheme | SpreadHybrid |
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| Def Scheme | D43 |
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| Offense | Overall - 720(11) : Pass - 486(9) : Rush - 234(14) |
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| Defense | Overall - 769(14) : Pass - 624(18) : Rush - 145(3) |
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| Leading Passer | Mike Ngo - 2953 |
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| Leading Rusher | Greg Bell - 1762 |
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| Leading Receiver | Terry Glenn - 1079 |
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| Leading Tackler | Lawrence Taylor - 145 |
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| Turnovers | 4 Take Aways / 0 Turn Overs (+4) |
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| Penalties | 11 For 100 Yards |
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| | Record | 1-1-0 (0-0-0 Home) |
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| Coach | Bulldog Turner |
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| Off Scheme | ProStyleHybrid |
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| Def Scheme | D43Hybrid |
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| Offense | Overall - 692(14) : Pass - 302(19) : Rush - 390(3) |
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| Defense | Overall - 591(2) : Pass - 453(12) : Rush - 138(1) |
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| Leading Passer | Vince Young - 3646 |
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| Leading Rusher | Marcus Allen - 1695 |
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| Leading Receiver | Miles Austin - 1393 |
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| Leading Tackler | Jon Beason - 182 |
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| Turnovers | 2 Take Aways / 7 Turn Overs (-5) |
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| Penalties | 9 For 57 Yards |
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| Last Game Starters |
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Buffalo Bills Offense| Quarterback | Mike Ngo |
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| Running Backs | Greg Bell - Tuffy Leemans |
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| Receivers | Marvin Harrison - Andre Reed |
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| Tight End | Pete Metzelaars |
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| Offensive Line | Anthony Munoz - Jahri Evans - Nick Mangold - Cam Jurgens - Eric Young |
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Buffalo Bills Defense
| Defensive Line | Reggie White - Russell Maryland - Darryl Grant - Simeon Rice |
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| Linebackers | Pat Swilling - Mike Singletary - Lawrence Taylor |
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| Cornerbacks | Everson Walls - Marcus Jones CB |
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| Safeties | Eugene Robinson - Roland James |
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| Kicker / Punter | Nick Novak - Jake Camarda |
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| New York Titans Offense| Quarterback | Vince Young |
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| Running Backs | Marcus Allen - Tim Spencer |
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| Receivers | Santonio Holmes - Miles Austin |
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| Tight End | Hoby Brenner |
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| Offensive Line | Stan Brock - Alan Faneca - Jeremy Cain - Daryn Colledge - Zach Strief |
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New York Titans Defense
| Defensive Line | Brent Williams - Mark Duda - Don Davey - Ray Childress |
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| Linebackers | Matt Millen - Jon Beason - Ron Rivera |
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| Cornerbacks | Kevin Ross - Andrew Booth Jr |
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| Safeties | Vince Albritton - Leonard Smith |
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| Kicker / Punter | Rich Karlis - Richmond McGee |
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| Injuries |
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Buffalo Bills Injuries
| Pete Metzelaars (TE) | Torn Miniscus (Out (1-2 weeks)) |
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| New York Titans Injuries
| Vince Albritton (FS) | Severe Migraines (Questionable) |
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| Santonio Holmes (WR) | Fractured Nose (Probable) |
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| Webster Slaughter (WR) | Sprained Ankle (Questionable) |
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