| The Buffalo Bills have demoted WR Khalil Shakir to the practice squad! |
| The Buffalo Bills have demoted LB Jesse Solomon to the practice squad! |
| The Buffalo Bills have demoted CB Christian Benford to the practice squad! |
| The Buffalo Bills have demoted T Ethan Brooks to the practice squad! |
| The Buffalo Bills have demoted G Willie Colon to the practice squad! |
| The Buffalo Bills release G Spencer Burford to free agency! |
| The Buffalo Bills have signed G Willie Colon from the free agent pool! |
| The Buffalo Bills release RB Jaylen Warren to free agency! |
| The Buffalo Bills release LB Nate Landman to free agency! |
| The Buffalo Bills release G Zachary Thomas to free agency! |
| The Buffalo Bills have signed G Terry Long from the free agent pool! |
| The Buffalo Bills have signed DE Robert Young from the free agent pool! |
| The Buffalo Bills have signed FB Randy McMillan from the free agent pool! |
| The Buffalo Bills release T Nicholas Petit-Frere to free agency! |
| The Buffalo Bills release CB Perry Phenix to free agency! |
| The Buffalo Bills have signed T Broderick Thompson from the free agent pool! |
| The Buffalo Bills have signed LB David Little from the free agent pool! |
| The Buffalo Bills have signed CB Dave Waymer from the free agent pool! |
| The Buffalo Bills have signed CB Everson Walls from the free agent pool! |
| The Buffalo Bills have signed SS Roland James in free agency! |
| The Buffalo Bills have drafted CB Perry Phenix! |
| The Buffalo Bills have drafted LB Jesse Solomon! |
| The Buffalo Bills have drafted DT Joe Phillips! |
| The Buffalo Bills have drafted QB Doug Flutie! |
| The Buffalo Bills have drafted G Mike Michalske! |
| The Buffalo Bills have drafted DT Tony Casillas! |
| The Buffalo Bills have drafted LB London Fletcher! |
| The Buffalo Bills have drafted LB Pat Swilling! |
| The Buffalo Bills have signed T Anthony Munoz in free agency! |
| The Buffalo Bills have signed K Nick Novak in free agency! |
| The Buffalo Bills have franchise tagged FB Tuffy Leemans! |
| The Buffalo Bills have traded C Doug Kramer to the Green Bay Packers! | |
| The Buffalo Bills have traded 1990 Round 5 pick - BUF to the Green Bay Packers! | |
| The Green Bay Packers have traded T Ethan Brooks to the Buffalo Bills! | |
| The Green Bay Packers have traded C Ikem Ekwonu to the Buffalo Bills! | |
| The Green Bay Packers have traded 1990 Round 6 pick - LON to the Buffalo Bills! | |
| The Buffalo Bills have traded RB O.J. Simpson to the Atlanta Falcons! | |
| The Buffalo Bills have traded WR Drake London to the Atlanta Falcons! | |
| The Buffalo Bills have traded TE Ernie Conwell to the Atlanta Falcons! | |
| The Buffalo Bills have traded LB Chip Banks to the Atlanta Falcons! | |
| The Buffalo Bills have traded LB John Mobley to the Atlanta Falcons! | |
| The Buffalo Bills have traded CB Johnathan Joseph to the Atlanta Falcons! | |
| The Buffalo Bills have traded 1990 Round 5 pick - ATL to the Atlanta Falcons! | |
| The Buffalo Bills have traded 1991 Round 3 pick - ATL to the Atlanta Falcons! | |
| The Atlanta Falcons have traded WR Marvin Harrison to the Buffalo Bills! | |
| The Buffalo Bills have traded K Nick Folk to the New York Giants! | |
| The Buffalo Bills have traded 1990 Round 7 pick - ATL to the New York Giants! | |
| The Buffalo Bills have traded T Daren Gilbert to the New York Titans! | |
| The Buffalo Bills have traded 1990 Round 7 pick - BUF to the New York Titans! | |
| The Buffalo Bills have activated WR Drake London from injured reserve! |
| The Buffalo Bills have demoted WR Khalil Shakir to the practice squad! |
| The Buffalo Bills have promoted T Daren Gilbert from the practice squad to the main roster! |
| The Buffalo Bills have demoted T Ken Lanier to the practice squad! |
| The Buffalo Bills have drafted P Jake Camarda! |
| The Buffalo Bills have drafted SS Nick Cross! |
| The Buffalo Bills have drafted QB Matt Corral! |
| The Buffalo Bills have drafted LB Boye Mafe! |
| The Buffalo Bills have drafted FS Elijah Hicks! |
| The Buffalo Bills have drafted WR Calvin Austin III! |
| The Buffalo Bills have drafted DE Devonte Wyatt! |
| The Buffalo Bills have drafted RB Kyren Williams! |
| The Buffalo Bills have drafted CB Kaiir Elam! |
| The Buffalo Bills have drafted G Cam Jurgens! |
| The Buffalo Bills have drafted CB Marcus Jones CB! |
| The Buffalo Bills have drafted LB Desmond Bishop! |
| The Buffalo Bills have drafted DT Derek Landri! |
| The Buffalo Bills have drafted RB Antonio Pittman! |
| The Buffalo Bills have drafted K Nick Folk! |
| The Buffalo Bills have drafted WR Mike Sims-Walker! |
| The Buffalo Bills have drafted WR Sidney Rice! |
| The Buffalo Bills have drafted T Eric Young! |
| The Buffalo Bills have drafted CB Mike Mickens! |
| The Buffalo Bills have signed RB Lorenzo Hampton from the free agent pool! |
| The Buffalo Bills have placed RB Gary Anderson on injured reserve! |
| The Buffalo Bills have demoted RB Eddie Lee Ivery to the practice squad! |
| The Buffalo Bills release G Randy Cross to free agency! |
| The Buffalo Bills have activated RB Gerald Willhite from injured reserve! |